Discovery of a novel monoclonal PD-L1 antibody H1A that promotes T-cell mediated tumor killing activity in renal cell carcinoma
Z. An, M. A. Hsu, J. K. Gicobi, T. Xu, S. M. Harrington, H. Zhang, K. D. Pavelko, J. B. Hirdler, C. Lohse, R. Nabavizadeh, R. R. Pessoa, V. Sharma, R. H. Thompson, B. C. Leibovich, H. Dong, F. Lucien
This study identifies a novel monoclonal PD-L1 antibody H1A that enhances T-cell mediated tumor killing in renal cell carcinoma compared to existing PD-1/PD-L1 inhibitors.
bioRxiv · Sep 10, 2022 · PreprintImmunology