Live-attenuated pediatric parainfluenza vaccine expressing 6P-stabilized SARS-CoV-2 spike protein is protective against SARS-CoV-2 variants in hamsters
X. Liu, H.-S. Park, Y. Matsuoka, C. Santos, L. Yang, C. Luongo, I. Moore, R. Johnson, N. Garza, P. Zhang, P. Lusso, S. Best, U. Buchholz, C. Le Nouën
This study compares two live-attenuated vaccines in hamsters, showing that B/HPIV3/S-6P induces stronger immune responses and better protection against SARS-CoV-2 variants than B/HPIV3/S-2P.
bioRxiv · Dec 12, 2022Microbiology