ImmunologybioRxiv
Deficiency of macrophage-derived Dnase1L3 causes lupus-like phenotypes in mice
M. Engavale, C. J. Hernandez, A. Infante…·P. A. Keyel
This study shows that reducing macrophage-derived Dnase1L3 in mice causes mild lupus-like symptoms, suggesting its role in preventing lupus.
DOI 10.1093/jleuko/qiad115