C. M. Stewart

This study identifies spatial localization as a key determinant of macrophage heterogeneity and self-renewal in breast cancer, with implications for therapeutic strategies.

This study identifies IL-4 as a regulator of CART cell exhaustion and shows that IL-4 neutralization improves antitumor efficacy.

This study uses deep mutational scanning to analyze how mutations in the Omicron BA.1 and BA.2 RBDs affect ACE2 binding, RBD folding, and antibody escape, identifying epistatic shifts and lineage-specific changes.

This study shows that sphingosine kinases (SKs) facilitate entry of late-penetrating viruses like Ebola and SARS-CoV-2 by promoting endocytic trafficking, and their inhibition blocks viral entry.

This study shows that female flour beetles adjust reproductive investment based on infection dose, shifting to somatic maintenance at lower doses and trade-off between offspring quality and quantity at higher doses.

This study identifies a MMP2/9-dependent entry pathway for SARS-CoV-2 and variants, showing differential usage and reduced activity in Omicron.