ImmunologybioRxivPreprint
Expression of a STING Gain-of-function Mutation in Endothelial Cells Initiates Lymphocytic Infiltration of the Lungs
K. M. Gao, K. Chiang, F. T. Korkmaz…·A. Marshak-Rothstein
This study shows that endothelial cells expressing a STING gain-of-function mutation drive immune cell infiltration and lung disease in mice, suggesting potential therapeutic targeting of endothelial STING.
DOI 10.1101/2023.07.27.550897