Cancer BiologybioRxiv
The paracaspase MALT1 controls cholesterol homeostasis in glioblastoma stem-like cells through lysosome proteome shaping
C. Maghe, K. Trillet, G. A. Gregoire…·J. Gavard
This study shows that MALT1 regulates cholesterol homeostasis in glioblastoma stem-like cells by shaping the lysosome proteome, leading to cell death when disrupted.
DOI 10.1016/j.celrep.2023.113631