In vivo evolution of a Klebsiella pneumoniae capsule defect promotes complement-mediated opsono-phagocytosis and persistence during recurrent infection
W. Bain, B. Ahn, H. Penaloza, C. McElheny, N. Tolman, R. van der Geest, S. Gonzalez-Ferrer, N. Chen, X. An, R. Hosuru, M. Tabary, E. Papke, N. Kohli, N. Farooq, W. Bachman, , J. Lee
The paper identifies a capsule defect in K. pneumoniae that enhances complement-mediated opsonophagocytosis and persistence during recurrent infections.
bioRxiv · May 31, 2023 · PreprintMicrobiology