Author

W. Bain

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

A. Iovleva· 1 shared A. Kaminski· 1 shared A. Morris· 1 shared A. R. Cillo· 1 shared A. Ray· 1 shared A. Sarkar· 1 shared A. Somasundaram· 1 shared A. Zhao· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperMicrobiology

A. Iovleva

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Damage sensing through TLR9 Regulates Inflammatory and Antiviral Responses During Influenza Infection

J. Kim, Y. Yuan, K. Agaronyan, A. Zhao, V. D. Wang, G. Gupta, H. Essayas, A. Kaminski, J. McGovern, S. Yu, S. Woo, C. J. Lee, S. Gandhi, T. Saber, T. Saleh, , L. Sharma

This study shows that TLR9 sensing of tissue damage during influenza infection promotes inflammation and antiviral responses, but its absence leads to impaired viral clearance and prolonged lung injury.

bioRxiv · Mar 4, 2024Immunology

In vivo evolution of a Klebsiella pneumoniae capsule defect promotes complement-mediated opsono-phagocytosis and persistence during recurrent infection

W. Bain, B. Ahn, H. Penaloza, C. McElheny, N. Tolman, R. van der Geest, S. Gonzalez-Ferrer, N. Chen, X. An, R. Hosuru, M. Tabary, E. Papke, N. Kohli, N. Farooq, W. Bachman, , J. Lee

The paper identifies a capsule defect in K. pneumoniae that enhances complement-mediated opsonophagocytosis and persistence during recurrent infections.

bioRxiv · May 31, 2023 · PreprintMicrobiology

Antibodies targeting conserved non-canonical antigens and endemic coronaviruses associate with favorable outcomes in severe COVID-19

S. P. Peddireddy, S. A. Rahman, A. R. Cillo, G. M. Vijay, A. Somasundaram, C. J. Workman, W. Bain, B. J. McVerry, B. Methe, J. S. Lee, P. Ray, A. Ray, T. C. Bruno, D. A. Vignali, G. D. Kitsios, , J. Das

The paper identifies antibody responses against non-canonical and endemic coronavirus antigens as predictors of favorable outcomes in severe COVID-19.

bioRxiv · Jan 24, 2022Immunology