Author

C. Meehan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Plant Biology· 2 Biochemistry· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Approach:statistical model· 3 Organism:Arabidopsis· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:development & morphogenesis· 2 Organism:human· 2 Assay:proteomics· 2 Assay:whole-genome sequencing· 2

Frequent Co-Authors

J. Gutierrez-Marcos· 2 shared A. Alruwaili· 1 shared A. Barbova· 1 shared A. Bhatt· 1 shared A. Cabibbe· 1 shared A. Dawson· 1 shared A. Dean· 1 shared A. Feher· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersPlant Biology

J. Gutierrez-Marcos

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Author profile →

6 papers

Recent·Most cited

A new method for the reproducible development of aptamers (Neomers)

C. Meehan, E. L. Hamilton, C. G. Mansour, S. Lecocq, C. J. Drake, Y. An, E. Rodrigues, G. Penner

This paper introduces a new aptamer selection method called Neomers, which improves reproducibility and specificity by mimicking immune tolerance through structured random nucleotide libraries.

bioRxiv · Dec 19, 2023Biochemistry

Predicting MmpR-based bedaquiline resistance using sequence- and structure-based features

E. Riviere, M. Safarpour, P. Meysman, B. Cuypers, C. Meehan, K. Laukens, A. van Rie

This paper develops a machine learning model to predict bedaquiline resistance using sequence and structural features of Rv0678 variants, achieving moderate performance but not sufficient for clinical use.

bioRxiv · Dec 19, 2022 · PreprintMicrobiology

Predictable and stable epimutations induced during clonal propagation with embryonic transcription factors

A. Wibowo, J. Antunez-Sanchez, A. Dawson, J. Price, C. Meehan, T. Wrightsman, M. Collenberg, I. Berzukov, C. Becker, M. Benhamed, D. Weigel, J. Gutierrez-Marcos

The paper investigates how epigenetic modifications during clonal propagation affect phenotypic variation in Arabidopsis thaliana, showing that tissue-specific DNA methylation imprints drive these changes.

bioRxiv · Mar 15, 2022 · PreprintPlant Biology

Characterization of genomic variants associated with resistance to bedaquiline and delamanid in naïve Mycobacterium tuberculosis clinical strains

S. Battaglia, A. Spitaleri, A. Cabibbe, C. Meehan, C. Utpatel, N. Ismail, S. Tahseen, A. Skrahina, N. Alikhanova, K. S. Mostofa, A. Barbova, S. Niemann, R. Groenheit, A. Dean, M. Zignol, , D. Cirillo

This study identifies genetic mutations associated with resistance to bedaquiline and delamanid in Mycobacterium tuberculosis strains using whole genome sequencing and in silico analysis.

bioRxiv · May 27, 2020Microbiology

Insights into ancestry and adaptive evolution of the Mycobacterium tuberculosis complex from analysis of the emerging pathogen Mycobacterium riyadhense

Q. Guan, M. Garbati, S. Mfarrej, T. AlMutairi, A. Smyth, A. Singh, S. Fagbo, J. Browne, M. A. urRahman, A. Alruwaili, A. Hoosen, C. Meehan, C. Nakajima, Y. Suzuki, A. Bhatt, , A. Pain

This paper characterizes the genome of Mycobacterium riyadhense, showing it shares ancestry with Mycobacterium tuberculosis and provides insights into the evolutionary path of the MTBC.

bioRxiv · Nov 8, 2019 · PreprintEvolutionary Biology

Two Receptor-Like Kinases Required For Arabidopsis Endodermal Root Organisation Shape The Rhizosphere Microbiome

J. Durr, G. Reyt, S. Spaepen, S. Hilton, C. Meehan, W. Qi, T. Kamiya, P. Flis, H. G. Dickinson, A. Feher, G. Bending, P. Schulze-Lefert, D. E. Salt, J. Gutierrez-Marcos

This study identifies ERK1 and RBK1 as key regulators of Casparian Strip formation in Arabidopsis, which in turn influences rhizosphere microbiome composition.

bioRxiv · Oct 24, 2019Plant Biology