Kinetic properties of optogenetic site-specific DNA recombination by LiCre-loxP
A. Dufour, H. Duplus-Bottin, T. Boukeke-Lesplulier, E. Casassa, G. Triqueneaux, L. Tarbouriech, C. Darthenay-Kiennemann, A. Dumont, C. Moali, F. Vittoz, D. Jost, G. Yvert
This paper characterizes the kinetic properties of the optogenetic LiCre-loxP system using in vitro and in vivo experiments, revealing temperature-dependent efficiency and a model for recombination synapse formation.
bioRxiv · May 17, 2024Bioengineering