C. Moparthy

Chronic activation of the aryl hydrocarbon receptor in muscle exacerbates ischemic pathology in chronic kidney disease

This study shows chronic AHR activation in muscle worsens ischemic damage in CKD and PAD by impairing muscle function and mitochondrial health.

IGF-1 therapy improves muscle size and function in experimental peripheral arterial disease

This study shows that IGF-1 therapy increases muscle size and strength in a rodent PAD model, with greater effects in female mice.