Author

C. N. Qi

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Immunology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

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C. L. Mackall· 1 shared C. Lamarche· 1 shared E. W. Weber· 1 shared G. Novakovsky· 1 shared M. K. Levings· 1 shared

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2020-2020 · peak 1/yr

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1 shared paperImmunology

C. L. Mackall

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1 paper

Recent·Most cited

ImmunologybioRxivPreprintJun 27, 2020

Repeated stimulation or tonic-signaling chimeric antigen receptors drive regulatory T cell exhaustion

C. Lamarche, G. Novakovsky, C. N. Qi…·M. K. Levings

This study shows that human regulatory T cells (Tregs) can become exhausted through repetitive stimulation or tonic-signaling CARs, reducing their suppressive function in vivo.

DOI 10.1101/2020.06.27.175158

humanbulk RNA-seq

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