MicrobiologybioRxivPreprint
An anti-CRISPR protein induces strong non-specific DNA binding activity in a CRISPR-Cas complex
W.-T. Lu, C. N. Trost, H. Muller-Esparza…·A. R. Davidson
This study shows that AcrIF9 enhances non-specific DNA binding in a CRISPR-Cas complex, which is conserved across homologues and suggests a new mechanism for Acr function.
DOI 10.1101/2020.05.28.119941