BiochemistrybioRxiv
Tryptophan fluorescence quenching in β-lactam-interacting proteins is modulated by the structure of intermediates and final products of the acylation reaction
S. Triboulet, Z. Edoo, F. Compain…·M. Arthur
This study shows that fluorescence quenching in β-lactam-interacting proteins depends on the structure of reaction intermediates and products, not direct Trp-drug interactions.
DOI 10.1021/acsinfecdis.9b00023