Cancer BiologybioRxiv
Anti-CD117 CAR T cells incorporating a safety switch eradicate human acute myeloid leukemia and hematopoietic stem cells
C. F. Magnani, R. Myburgh, S. Brunn…·M. G. Manz
This study develops anti-CD117 CAR T cells with a safety switch to target and eliminate acute myeloid leukemia and hematopoietic stem cells in preclinical models.