Fishing for contact: Modeling perivascular glioma invasion in the zebrafish brain.
R. A. Umans, M. ten Kate, C. Pollock, H. Sontheimer
This study uses zebrafish to model perivascular GBM invasion, showing that tumor cells can co-opt blood vessels in the CNS and that Wnt signaling inhibition disrupts these interactions.
bioRxiv · Aug 15, 2020Cancer Biology