J. Campbell

A role for fibroblast-derived SASP factors in the activation of pyroptotic cell death in mammary epithelial cells

This study shows that senescent fibroblast-secreted factors induce pyroptotic cell death in mammary epithelial cells, independent of oncogenic signaling.

Cellular, Molecular, and Enzymatic Signatures ofThrombi are Vascular Bed-Dependent

This study compares cellular and enzymatic features of arterial and venous thrombi from different vascular beds, finding distinct molecular profiles and enzyme activities linked to vascular remodeling.

Insights into Early Word Comprehension: Tracking the Neural Representations of Word Semantics in Infants.

The paper uses machine learning to decode semantic representations of words in infants' EEG data, finding age-related differences in decoding performance and generalization across age groups.

Inactivation of the Hippo Tumor Suppressor Pathway Promotes Melanoma

This study shows that the Hippo tumor suppressor pathway is activated in growth-arrested melanocytes, preventing melanoma development, and its inactivation allows BRAF-driven melanoma formation.

Helicobacter pylori accelerates KRAS-dependent gastric dysplasia

This study shows that Helicobacter pylori infection accelerates KRAS-driven gastric dysplasia in mice by promoting inflammation, altering gene expression, and increasing proliferation of preneoplastic glands.

Ungulate Responses to Unmanned Aerial Vehicles Flying at Different Altitudes in Africas Arid Savanna

This study examines how different flight altitudes of UAVs affect the behavioral responses of various ungulates in Namibia's arid savanna, finding strong correlations between altitude and response with some habituation observed.

Non-invasive real-time imaging of reactive oxygen species (ROS) using multispectral auto-fluorescence imaging technique: a novel tool for redox biology

This paper introduces a non-invasive, real-time imaging technique for detecting reactive oxygen species (ROS) using multispectral autofluorescence imaging, validated across multiple cell types and tissues.

A novel antibody targeting ICOS increases intratumoural cytotoxic to regulatory T cell ratio and induces tumour regression.

This paper develops an antibody targeting ICOS that improves the TEFF:TReg ratio and induces tumour regression in preclinical models.

Re-modeling of foliar membrane lipids in a seagrass allows for growth in phosphorus deplete conditions

The paper analyzes lipidome changes in seagrass leaves under high and low phosphorus conditions, identifying lipid species that adjust to phosphorus availability.

Genome-wide and high-density CRISPR-Cas9 screens identify point mutations in PARP1 causing PARP inhibitor resistance

The paper identifies PARP1 point mutations causing PARP inhibitor resistance through CRISPR-Cas9 screens and shows their impact on PARP1 trapping and chemotherapy sensitivity.

CancerGD: a resource for identifying and interpreting genetic dependencies in cancer

CancerGD identifies and interprets genetic dependencies in cancer by integrating genotypic profiling with loss-of-function screens in tumor cell lines.