Author

C. Pontious

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

A. Biankin· 1 shared B. Nelson· 1 shared C. A. Lyssiotis· 1 shared C. J. Halbrook· 1 shared D. Chang· 1 shared D. M. Kremer· 1 shared H. C. Crawford· 1 shared H. Hong· 1 shared

Activity by Year

2018-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. Biankin

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1 paper

Recent·Most cited

Macrophage Released Pyrimidines Inhibit Gemcitabine Therapy in Pancreatic Cancer

C. J. Halbrook, C. Pontious, H.-J. Lee, I. Kovalenko, Y. Zhang, L. Lapienyte, S. Dreyer, D. M. Kremer, P. Sajjakulnukit, L. Zhang, B. Nelson, H. Hong, S. Kemp, D. Chang, A. Biankin, , C. A. Lyssiotis

This study shows macrophages in pancreatic cancer release pyrimidines that inhibit gemcitabine therapy by competing with the drug for uptake and metabolism, and reducing macrophage burden improves treatment response.

bioRxiv · Nov 5, 2018Cancer Biology