Ras/MAPK signalling intensity defines subclonal fitness in a mouse model of primary and metastatic hepatocellular carcinoma
A. Lozano, F.-R. Souche, C. Ramirez, S. Vegna, G. Desandre, A. Riviere, V. Dardalhon, A. Zine El Aabidine, P. Fort, L. Akkari, U. Hibner, D. Gregoire
This study shows that varying levels of MAPK Erk signaling in Ras-transformed cells influence tumor growth and immune evasion in a mouse model of hepatocellular carcinoma.
bioRxiv · Aug 13, 2021Cancer Biology