Mechanisms of Nuclear Pore Complex disassembly by the mitotic Polo-Like Kinase 1 (PLK-1) in C. elegans embryos
S. Nkombo Nkoula, G. Velez-Aguilera, B. Ossareh-Nazari, L. Van Hove, C. Ayuso, V. Legros, G. Chevreux, L. Thomas, G. Seydoux, P. Askjaer, L. PINTARD
The paper identifies how PLK-1 dismantles nuclear pore complexes in C. elegans zygotes by phosphorylating intrinsically disordered regions of nucleoporins.
bioRxiv · Feb 21, 2023 · PreprintCell Biology