ATF6 activation alters colonic lipid metabolism causing tumor-associated microbial adaptation
O. I. Coleman, A. Sorbie, A. Riva, M. von Stern, S. Kuhls, D. Selegato, N. Koehler, J. Wirbel, T. Kacprowski, A. Dunkel, J. K. Pauling, J. Plagge, D. Miedel-Cuadra, S. Wagner, I. Chadly, , D. Haller
This study shows ATF6 activation in colonic epithelial cells alters lipid metabolism, promoting tumor-associated microbial adaptation in mice and human colorectal cancer patients.
bioRxiv · Nov 3, 2023 · PreprintCancer Biology