Author

C. Roecken

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

P. Rosenstiel· 2 shared A. Dunkel· 1 shared A. Riva· 1 shared A. Sorbie· 1 shared C. Kaleta· 1 shared C. Roeder· 1 shared C. Schafmayer· 1 shared C. Schmidt· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

P. Rosenstiel

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Hexokinase 2 expression in apical enterocytes correlates with inflammation severity in patients with inflammatory bowel disease

S. Weber-Stiehl, J. Taubenheim, L. Jaerke, C. Roecken, S. Schreiber, K. Aden, C. Kaleta, P. Rosenstiel, F. Sommer

The paper examines the relationship between HK2 expression and inflammation severity in IBD patients using bulk transcriptome data and confirms findings at the cellular and protein levels.

bioRxiv · Apr 4, 2024Immunology

ATF6 activation alters colonic lipid metabolism causing tumor-associated microbial adaptation

O. I. Coleman, A. Sorbie, A. Riva, M. von Stern, S. Kuhls, D. Selegato, N. Koehler, J. Wirbel, T. Kacprowski, A. Dunkel, J. K. Pauling, J. Plagge, D. Miedel-Cuadra, S. Wagner, I. Chadly, , D. Haller

This study shows ATF6 activation in colonic epithelial cells alters lipid metabolism, promoting tumor-associated microbial adaptation in mice and human colorectal cancer patients.

bioRxiv · Nov 3, 2023 · PreprintCancer Biology

Breaking the Crosstalk of the Cellular Tumorigenic Network in NSCLC by a Highly Effective Drug Combination

D. Guergen, T. Conrad, M. Becker, S. Sebens, C. Roecken, J. Hoffmann, S. Langhammer

This study shows a low-dose drug combination effectively suppresses NSCLC PDX tumors with high response and complete remission rates.

bioRxiv · Oct 23, 2021 · PreprintCancer Biology