Author

C. S. Elcombe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:development & morphogenesis· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Monteiro· 2 shared M. Bellingham· 2 shared M. Ghasemzadeh-Hasankolaei· 2 shared K. Sinclair· 1 shared M. R. Elcombe· 1 shared N. Evans· 1 shared N. P. Evans· 1 shared R. Lea· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 28 mutual co-author links

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2 shared papersPharmacology & Toxicology

A. Monteiro

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2 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivDec 9, 2022

Developmental exposure to a real-life environmental chemical mixture alters testicular transcription factor expression in neonatal and pre-pubertal rams, with morphological changes persisting into adulthood

C. S. Elcombe, A. Monteiro, M. Ghasemzadeh-Hasankolaei…·M. Bellingham

DOI 10.1016/j.etap.2023.104152

experimental assaydevelopment & morphogenesis

𝕏 PostBluesky

Pharmacology & ToxicologybioRxivFeb 8, 2022

Testicular Dysgenesis Syndrome-like morphology and gene expression, and activation of Hypoxia Inducible Factor 1 Alpha in juvenile lamb testes following developmental exposure to low-level environmental chemical mixture.

C. S. Elcombe, A. Monteiro, M. R. Elcombe…·M. Bellingham

This study shows that gestational exposure to a chemical mixture in sheep leads to testicular abnormalities and gene expression changes similar to human testicular dysgenesis syndrome.

DOI 10.1016/j.etap.2022.103913

bulk RNA-seqexperimental assay

𝕏 PostBluesky