ImmunologybioRxivPreprint
Identification of a unique TCR repertoire, consistent with a superantigen selection process in Children with Multi-system Inflammatory Syndrome
R. A. Porritt, L. Paschold, M. Noval Rivas…·M. Arditi
This study identifies a skewed TCR repertoire in MIS-C patients, with TRBV11-2 expansion linked to disease severity and superantigen-like interactions with SARS-CoV-2 spike protein.