Author

C. Sauer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Assay:whole-genome sequencing· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:ecology & biodiversity· 1

Frequent Co-Authors

A. Piskorz· 2 shared D. Sanders· 2 shared F. Correia Martins· 2 shared J. D. Brenton· 2 shared K. Hosking· 2 shared M. Jimenez-Linan· 2 shared M. Vias· 2 shared A. Amirthanayagam· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCancer Biology

A. Piskorz

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Siderophore piracy enables the nasal commensal Staphylococcus lugdunensis to antagonize the pathogen Staphylococcus aureus

R. Rosenstein, B. O. T. Salazar, C. Sauer, S. Heilbronner, B. Krismer, A. Peschel

This study shows that Staphylococcus lugdunensis reduces S. aureus colonization by producing lugdunin, and that mutualistic interactions with other commensals enhance its growth through siderophore piracy.

bioRxiv · Feb 29, 2024 · PreprintMicrobiology

Predicting response to cytotoxic chemotherapy

J. Thompson, L. Madrid, B. Hernando, C. Sauer, M. Vias, M. Escobar-Rey, W.-K. Leung, J. Huckstep, M. Sekowska, K. Hosking, M. Jimenez-Linan, M. Reinius, H. Dobson, D. De Silva, A. Fernandez-Sanroman, , G. Macintyre

This study develops three precision biomarkers based on chromosomal instability signatures to predict response to different chemotherapies, showing improved progression-free survival in clinical trials.

bioRxiv · Jan 28, 2023Cancer Biology

Somatic chromosomal number alterations affecting driver genes inform in-vitro and clinical drug response in high-grade serous ovarian cancer

F. Correia Martins, D.-L. Couturier, I. Santiago, C. Sauer, M. Vias, M. Angelova, D. Sanders, A. Piskorz, J. Hall, K. Hosking, A. Amirthanayagam, S. Cosulich, L. Carnevalli, B. Davies, T. B. K. Watkins, , J. D. Brenton

This study shows that somatic copy number alterations in driver genes correlate with drug response in HGSOC spheroid models and clinical settings.

bioRxiv · Oct 4, 2020 · PreprintCancer Biology