Author

D. De Silva

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Biochemistry· 1 Microbiology· 1 Scientific Communication & Education· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:statistical model· 3 Approach:experimental assay· 2 Organism:human· 2 Assay:whole-genome sequencing· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Organism:chicken / avian· 1 Research Focus:clustering· 1

Frequent Co-Authors

F. Markowetz· 2 shared G. Macintyre· 2 shared J. D. Brenton· 2 shared M. Jimenez-Linan· 2 shared A. C. Banyard· 1 shared A. Clamp· 1 shared A. Fernandez-Sanroman· 1 shared A. Hanif· 1 shared

Activity by Year

2017-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

F. Markowetz

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Consideration of sex as a biological variable in diabetes research across twenty years

C. M. Cherian, H. Reeves, D. De Silva, S. Tsao, K. E. Marshall, E. J. Rideout

This study assesses the inclusion of biological sex in diabetes research over 20 years, finding less than 15% of papers used sex-based analysis and highlighting the need for improved consideration of sex as a variable.

bioRxiv · Jun 13, 2023Scientific Communication & Education

The role of airborne particles in the epidemiology of clade 2.3.4.4b H5N1 high pathogenicity avian influenza virus in commercial poultry production units

J. James, C. J. Warren, D. De Silva, T. Lewis, K. Grace, S. M. Reid, M. Falchieri, I. H. Brown, A. C. Banyard

The paper investigates airborne transmission of clade 2.3.4.4b H5N1 HPAIV in poultry units, finding that infectious virus can travel short distances but not between premises, suggesting biosecurity measures are more critical.

bioRxiv · Mar 16, 2023Microbiology

Predicting response to cytotoxic chemotherapy

J. Thompson, L. Madrid, B. Hernando, C. Sauer, M. Vias, M. Escobar-Rey, W.-K. Leung, J. Huckstep, M. Sekowska, K. Hosking, M. Jimenez-Linan, M. Reinius, H. Dobson, D. De Silva, A. Fernandez-Sanroman, , G. Macintyre

This study develops three precision biomarkers based on chromosomal instability signatures to predict response to different chemotherapies, showing improved progression-free survival in clinical trials.

bioRxiv · Jan 28, 2023Cancer Biology

Validated B vitamin quantification from lentils by selected reaction monitoring mass spectrometry

H. Zhang, D. De Silva, D. Dissanayaka, T. D. WARKENTIN, A. Vandenberg

The paper develops a UPLC-SRM MS method to quantify B vitamins in lentils, finding a 1.5-fold increase in total B vitamins during germination with vitamin B5 as the most abundant.

bioRxiv · Oct 4, 2020Biochemistry

Copy-number signatures and mutational processes in ovarian carcinoma

G. Macintyre, T. Goranova, D. De Silva, D. Ennis, A. M. Piskorz, M. Eldridge, D. Sie, L.-A. Lewsley, A. Hanif, C. Wilson, S. Dowson, R. M. Glasspool, M. Lockley, E. Brockbank, A. Montes, , J. D. Brenton

This study identifies copy-number signatures in ovarian cancer and links them to mutational processes, showing that most cases involve multiple processes, suggesting therapeutic challenges.

bioRxiv · Sep 4, 2017Cancer Biology