TET1 and TDG suppress intestinal tumorigenesis by down regulating the inflammatory and immune response pathways
R. Tricarico, J. Madzo, G. Scher, S. Maegawa, J. Jelinek, C. Scher, W.-C. Chang, E. Nicolas, Y. Zhou, M. Slifker, K. Devarajan, K. Q. Cai, P. Nakajima, J. Xu, P. Mancuso, , A. Bellacosa
This study shows that TET1 and TDG reduce intestinal tumor formation by suppressing inflammatory and immune response pathways through DNA demethylation.
bioRxiv · Jun 21, 2019 · PreprintCancer Biology