Author

P. Mancuso

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1

Frequent Co-Authors

A. Bellacosa· 1 shared A. Raveane· 1 shared C. Scher· 1 shared E. Koltsova· 1 shared E. Nicolas· 1 shared F. Bertolini· 1 shared G. Mitola· 1 shared G. Scher· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. Bellacosa

Mutual co-authors in cluster

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2 papers

Recent·Most cited

A single-cell transcriptomic landscape of innate and adaptive intratumoral immunity in triple negative breast cancer during chemo- and immunotherapies

L. Carpen, P. Falvo, S. Orecchioni, G. Mitola, R. Hillje, S. Mazzara, P. Mancuso, S. Pileri, A. Raveane, F. Bertolini

This study uses scRNA-seq to analyze immune cell populations in TNBC mouse models during chemotherapy and immunotherapy, identifying changes in T cell exhaustion, macrophage polarization, and B cell activity.

bioRxiv · Dec 1, 2021Cancer Biology

TET1 and TDG suppress intestinal tumorigenesis by down regulating the inflammatory and immune response pathways

R. Tricarico, J. Madzo, G. Scher, S. Maegawa, J. Jelinek, C. Scher, W.-C. Chang, E. Nicolas, Y. Zhou, M. Slifker, K. Devarajan, K. Q. Cai, P. Nakajima, J. Xu, P. Mancuso, , A. Bellacosa

This study shows that TET1 and TDG reduce intestinal tumor formation by suppressing inflammatory and immune response pathways through DNA demethylation.

bioRxiv · Jun 21, 2019 · PreprintCancer Biology