Characterization and contribution of RPE senescence to Age-related macular degeneration in Tnfrsf10 knock out mice
I. WADA, K. Mori, P. G. Sreekumar, R. Ji, C. Spee, E. Hone, K. Ishikawa, K.-H. Sonoda, R. Kannan
This study investigates how RPE senescence contributes to AMD using TNFRSF10A silenced hRPE cells and Tnfrsf10 KO mice, showing increased p16 and p21 expression and metabolic changes.
bioRxiv · Aug 4, 2023 · PreprintPathology