PathologybioRxivPreprint
Characterization and contribution of RPE senescence to Age-related macular degeneration in Tnfrsf10 knock out mice
I. WADA, K. Mori, P. G. Sreekumar…·R. Kannan
This study investigates how RPE senescence contributes to AMD using TNFRSF10A silenced hRPE cells and Tnfrsf10 KO mice, showing increased p16 and p21 expression and metabolic changes.
DOI 10.1101/2023.08.04.552052