Author

C. T. Chaton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:protein structure prediction· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

K. V. Korotkov· 4 shared A. B. Herr· 2 shared A. E. Yarawsky· 2 shared N. Korotkova· 2 shared R. W. Reed· 2 shared A. H. A. Parret· 1 shared A. R. Horswill· 1 shared A. T. Tuukkanen· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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4 shared papersBiochemistry

K. V. Korotkov

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Mechanistic basis of staphylococcal interspecies competition for skin colonization

J. J. Maciag, C. Chantraine, K. B. Mills, R. Yadav, A. E. Yarawsky, C. T. Chaton, D. Vinod, N. C. Fitzkee, M. Mathelie-Guinlet, Y. F. Dufrene, P. D. Fey, A. R. Horswill, A. B. Herr

This study investigates the structural and functional basis of staphylococcal adhesion to skin and reveals cross-inhibition between S. epidermidis and S. aureus.

bioRxiv · Jan 26, 2023 · PreprintMicrobiology

Modification of cell wall polysaccharide spatially controls cell division in Streptococcus mutans

S. Zamakhaeva, C. T. Chaton, J. S. Rush, S. Ajay Castro, A. E. Yarawsky, A. B. Herr, N. M. van Sorge, H. C. Dorfmueller, G. I. Frolenkov, K. V. Korotkov, N. Korotkova

This study shows that GroP-deficient immature SCCs spatially coordinate AtlA and MapZ localization in S. mutans, ensuring proper cell division and morphology.

bioRxiv · Jun 26, 2020Microbiology

PE5-PPE4-EspG3 trimer structure from mycobacterial ESX-3 secretion system gives insight into cognate substrate recognition by ESX systems

Z. A. Williamson, C. T. Chaton, W. A. Ciocca, N. Korotkova, K. V. Korotkov

The paper presents the crystal structure of a PE5-PPE4-EspG3 trimer from the ESX-3 system, revealing unique interactions and structural dynamics compared to the ESX-5 system.

bioRxiv · Jan 16, 2020Biochemistry

Structural analysis of mycobacterial homoserine transacetylases central to methionine biosynthesis reveals druggable active site

C. T. Chaton, E. S. Rodriguez, R. W. Reed, J. Li, C. W. Kenner, K. V. Korotkov

The paper determines the crystal structures of three homoserine transacetylases and identifies MtMetX as highly druggable.

bioRxiv · Dec 10, 2019Biochemistry

Structural variability of EspG chaperones from mycobacterial ESX-1, ESX-3 and ESX-5 type VII secretion systems

A. T. Tuukkanen, D. Freire, S. Chan, M. A. Arbing, R. W. Reed, T. J. Evans, G. Zenkeviciute, J. Kim, S. Kahng, M. R. Sawaya, C. T. Chaton, M. Wilmanns, D. Eisenberg, A. H. A. Parret, K. V. Korotkov

The paper reports crystal and SAXS structures of EspG chaperones from mycobacterial ESX systems, revealing structural variability and potential substrate binding modes.

bioRxiv · Oct 13, 2018Biochemistry