Efficient megakaryopoiesis and platelet production require phospholipid remodeling and PUFA uptake through CD36
M. N. Barrachina, G. Pernes, I. C. Becker, I. Allaeys, T. I. Hirsch, D. J. Groeneveld, A. O. Khan, D. Freire, K. Guo, E. Carminita, P. K. Morgan, T. J. Collins, N. Mellett, Z. Wei, I. Almazni, , K. R. Machlus
This study identifies the role of phospholipid remodeling and PUFA uptake via CD36 in megakaryopoiesis and platelet production, showing dietary fatty acids impact platelet counts.
bioRxiv · Feb 12, 2023Cell Biology