C. Tastan

Precision Genome Editing Unveils a Breakthrough in Reversing Antibiotic Resistance: CRISPR/Cas9 Targeting of Multi-Drug Resistance Genes in Methicillin-Resistant Staphylococcus aureus

This study uses CRISPR/Cas9 to target and reduce antibiotic resistance genes in MRSA, significantly decreasing resistance to multiple antibiotics.

Phytohemagglutinin-Activated CAR-T Cells: Prolonged Persistence and Enhanced Anti-Tumor Response in CD19-Specific Acute Lymphoblastic Leukemia

This paper develops and tests two CD19-specific CAR-T cell designs, showing that PHA-activated CAR19BB-T cells provide prolonged persistence and enhanced anti-tumor effects in preclinical models of ALL.

CAR-T Cells with Phytohemagglutinin (PHA) Provide Anti-Cancer Capacity with Better Proliferation, Rejuvenated Effector Memory, and Reduced Exhausted T Cell Frequencies

This study shows that using Phytohemagglutinin (PHA) to activate CAR-T cells increases their proliferation, memory T cell populations, and anti-cancer efficacy compared to aCD3/aCD28 activation.

3D Digitizing An Animal Organ Could Make It Possible To Work With Anatomy Classes In The Metaverse Or With A 3D-Printed Real-Scale Organ On Demand

This paper demonstrates a method to 3D digitize animal organs using free mobile apps, enabling use in anatomy education and 3D printing for research and clinical applications.

Gamma-irradiated SARS-CoV-2 vaccine candidate, OZG-38.61.3, confers protection from SARS-CoV-2 challenge in human ACEII-transgenic mice

This paper describes an inactivated SARS-CoV-2 vaccine candidate, OZG-38.61.3, that provides protection in human ACE2-transgenic mice through gamma irradiation and intradermal administration.

Preliminary report of preclinical efficacy and safety analysis of gamma-irradiated inactivated SARS-CoV-2 vaccine candidates, SK-01 version 1 and OZG-3861 version 1

This study evaluates the safety and immunogenicity of two gamma-irradiated inactivated SARS-CoV-2 vaccines in mice, showing significant antibody and T cell responses without antibody-dependent enhancement.

SARS-CoV-2 Isolation and Propagation from Turkish COVID-19 patients

The paper isolates and characterizes SARS-CoV-2 from Turkish COVID-19 patients, providing methodology for virus propagation and cell culture tropism.