Cancer BiologyVaccinesPeer-reviewed
CAR-T Cells with Phytohemagglutinin (PHA) Provide Anti-Cancer Capacity with Better Proliferation, Rejuvenated Effector Memory, and Reduced Exhausted T Cell Frequencies
G. Gulden, B. Sert, T. Teymur…·C. Tastan
This study shows that using Phytohemagglutinin (PHA) to activate CAR-T cells increases their proliferation, memory T cell populations, and anti-cancer efficacy compared to aCD3/aCD28 activation.
DOI 10.3390/vaccines11020313