Author

E. Ovali

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cancer Biology· 1 Microbiology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1

Frequent Co-Authors

C. Tastan· 5 shared B. Yurtsever· 4 shared D. Cakirsoy· 3 shared D. Dilek Kancagi· 3 shared G. Tumentemur· 3 shared M. Acikel Elmas· 3 shared R. D. Turan· 3 shared S. Abanuz· 3 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersImmunology

C. Tastan

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

The Effect of Amniotic Fluid On Haıir Follicle Growth

G. Tumentemur, E. G. Aygun, B. Yurtsever, D. Cakirsoy, E. Ovali

This study investigates the efficacy and safety of frozen amniotic fluid and gamma-irradiated frozen amniotic fluid in promoting hair follicle growth in a rat hair loss model.

bioRxiv · Sep 8, 2023 · PreprintPathology

Phytohemagglutinin-Activated CAR-T Cells: Prolonged Persistence and Enhanced Anti-Tumor Response in CD19-Specific Acute Lymphoblastic Leukemia

B. Sert, G. Gulden, T. Teymur, Y. Ay, R. D. Turan, O. M. Unaldi, E. Guzenge, H. E. Erdil, S. Isik, P. Oz, I. Bozkurt, T. Arpaci, O. Kamali, E. Ovali, N. Tarhan, C. Tastan

This paper develops and tests two CD19-specific CAR-T cell designs, showing that PHA-activated CAR19BB-T cells provide prolonged persistence and enhanced anti-tumor effects in preclinical models of ALL.

bioRxiv · Jul 15, 2023 · PreprintImmunology

CAR-T Cells with Phytohemagglutinin (PHA) Provide Anti-Cancer Capacity with Better Proliferation, Rejuvenated Effector Memory, and Reduced Exhausted T Cell Frequencies

G. Gulden, B. Sert, T. Teymur, Y. Ay, N. N. Tiryaki, E. Ovali, N. Tarhan, C. Tastan

This study shows that using Phytohemagglutinin (PHA) to activate CAR-T cells increases their proliferation, memory T cell populations, and anti-cancer efficacy compared to aCD3/aCD28 activation.

Vaccines · Jan 31, 2023Peer-reviewedCancer Biology

Gamma-irradiated SARS-CoV-2 vaccine candidate, OZG-38.61.3, confers protection from SARS-CoV-2 challenge in human ACEII-transgenic mice

R. D. Turan, C. Tastan, D. Dilek Kancagi, B. Yurtsever, G. Sir Karakus, S. Ozer, S. Abanuz, D. Cakirsoy, G. Tumentemur, S. Demir, U. Seyis, R. Kuzay, M. Elek, M. E. Kocaoglu, G. Ertop, , E. Ovali

This paper describes an inactivated SARS-CoV-2 vaccine candidate, OZG-38.61.3, that provides protection in human ACE2-transgenic mice through gamma irradiation and intradermal administration.

bioRxiv · Oct 28, 2020Immunology

Preliminary report of preclinical efficacy and safety analysis of gamma-irradiated inactivated SARS-CoV-2 vaccine candidates, SK-01 version 1 and OZG-3861 version 1

G. SIR KARAKUS, C. Tastan, D. Dilek Kancagi, B. Yurtsever, G. Tumentemur, S. Demir, R. D. Turan, S. Abanuz, D. Cakirsoy, U. Seyis, S. Ozer, O. Elibol, M. Elek, G. Ertop, S. Arbak, , E. Ovali

This study evaluates the safety and immunogenicity of two gamma-irradiated inactivated SARS-CoV-2 vaccines in mice, showing significant antibody and T cell responses without antibody-dependent enhancement.

bioRxiv · Sep 4, 2020 · PreprintImmunology

SARS-CoV-2 Isolation and Propagation from Turkish COVID-19 patients

C. Tastan, B. Yurtsever, G. Sir, D. Dilek Kancagi, S. Demir, S. Abanuz, U. Seyis, M. Yildirim, R. Kuzay, O. Elibol, S. Arbak, M. Acikel Elmas, S. Birdogan, E. Sahin, O. Ozcan, , E. Ovali

The paper isolates and characterizes SARS-CoV-2 from Turkish COVID-19 patients, providing methodology for virus propagation and cell culture tropism.

bioRxiv · Apr 23, 2020Microbiology