ImmunologybioRxivPreprint
Phytohemagglutinin-Activated CAR-T Cells: Prolonged Persistence and Enhanced Anti-Tumor Response in CD19-Specific Acute Lymphoblastic Leukemia
B. Sert, G. Gulden, T. Teymur…·C. Tastan
This paper develops and tests two CD19-specific CAR-T cell designs, showing that PHA-activated CAR19BB-T cells provide prolonged persistence and enhanced anti-tumor effects in preclinical models of ALL.
DOI 10.1101/2023.07.15.547808