Deconvolution Of Hematopoietic Stem/Progenitor Cell Signaling Predicts Inflammatory Niche Remodeling To Be A Determinant Of Tissue Failure And Outcome In Human AML
L. Chen, E. Pronk, C. van Dijk…·M. Raaijmakers
The paper uses scRNA-seq to analyze signaling between hematopoietic stem/progenitor cells and their niches in AML, identifying inflammatory niche remodeling as a factor affecting tissue failure and patient outcome.