Cytoplasmic CPSF6 regulates HIV-1 capsid trafficking and infection in a cyclophilin A-dependent manner
Z. Zhong, J. Ning, E. A. Boggs, S. Jang, C. Wallace, C. Telmer, M. Bruchez, J. Ahn, A. Engelman, p. zhang, S. C. Watkins, Z. Ambrose
The paper shows CPSF6 and CypA interact to regulate HIV-1 capsid trafficking and infection by affecting capsid-CPSF6 complex formation and stability.
bioRxiv · Jun 5, 2020Microbiology