Efficient 5-OP-RU-induced enrichment of Mucosal-associated invariant T cells in the murine lung does not enhance control of aerosol Mycobacterium tuberculosis infection.
C. Vorkas, O. Levy, M. S. Skular, K. Li, J. Aube, M. S. Glickman
This study shows that priming MAIT cells in mice with 5-OP-RU and P2C increases their activation and expansion but does not improve control of Mtb infection.
bioRxiv · Aug 19, 2020Immunology