Transcription factor TAp73 and microRNA-449 complement each other to support multiciliogenesis
M. Wildung, T. U. Esser, K. B. Grausam, C. Wiedwald, L. Volceanov-Hahn, D. Riedel, S. Beuermann, L. Li, J. L. S. Zylla, A.-K. Guenther, M. Wienken, E. Ercetin, Z. Han, F. Bremmer, O. Shomroni, , M. Lize
The paper shows TAp73 and miR449 work together to support multiciliogenesis, with their combined loss causing brain defects and hydrocephalus.
bioRxiv · Dec 19, 2018Cell Biology