Mechanical stress compromises multicomponent efflux complexes in bacteria
L. A. Genova, M. F. Roberts, Y.-C. Wong, C. E. Harper, A. G. Santiago, B. Fu, A. Srivastava, W. Jung, L. M. Wang, Łukasz Krzeminski, X. Mao, X. Sun, C.-Y. Hui, P. Chen, C. Hernandez
The paper shows mechanical stress, specifically shear stress, disrupts the CusCBA efflux complex in E. coli, increasing metal toxicity susceptibility.
bioRxiv · Mar 8, 2019Biophysics