Author

W. Jung

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 4 Immunology· 2 Animal Behavior & Cognition· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 3 Organism:E. coli· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Assay:behavioral assay· 1

Frequent Co-Authors

P. Chen· 3 shared D. Kim· 2 shared A. G. Santiago· 1 shared A. Roland· 1 shared A. Srivastava· 1 shared B. Fu· 1 shared C. E. Harper· 1 shared C. G. Hubert· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersBiophysics

P. Chen

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Compartment-Specific Antibody Correlates of Protection to SARS-CoV-2 Omicron in Macaques

X. Tong, Q. Wang, W. Jung, T. M. Chicz, R. Blanc, L. J. Parker, D. H. Barouch, R. P. McNamara

This study identifies compartment-specific antibody correlates of protection against SARS-CoV-2 Omicron in macaques, showing neutralizing antibodies in serum and antibody-dependent cellular phagocytosis in bronchiolar lavage are strongest correlates.

bioRxiv · Mar 1, 2024Immunology

A "through-DNA" mechanism for metal uptake-vs.-efflux regulation

U. K. Chakraborty, Y. Park, K. Sengupta, W. Jung, C. Joshi, D. H. Francis, P. Chen

The paper reveals a through-DNA mechanism where ZntR influences Zur's DNA binding kinetics, enabling coordinated metal uptake and efflux regulation in E. coli.

bioRxiv · Dec 5, 2023 · PreprintBiophysics

Evaluation of mouse behavioral responses to nutritive versus nonnutritive sugar using a deep learning-based 3D real-time pose estimation system

J. Kim, D. Kim, W. Jung, G. S. B. Suh

The paper uses a deep learning system to analyze mouse behavior toward nutritive and nonnutritive sugar, finding distinct behavioral responses before licking.

bioRxiv · Sep 19, 2022Animal Behavior & Cognition

How to use transcriptomic data for game-theoretic modeling of treatment-induced resistance in cancer cells? A case study in patient-derived glioblastoma organoids

L. Spekking, C. Lokh, W. Jung, M. Verduin, S. Azimi, C. G. Hubert, M. Vooijs, R. Cavill, K. Stankova

This paper uses transcriptomic data from glioblastoma organoids to predict evolutionary responses to irradiation using game-theoretic models, finding hypoxia drives short-term resistance while supervised methods best estimate evolutionary dynamics.

bioRxiv · Jan 26, 2022 · PreprintCancer Biology

Development of spike receptor-binding domain nanoparticle as a vaccine candidate against SARS-CoV-2 infection in ferrets

Y.-I. Kim, D. Kim, K.-M. Yu, H. D. Seo, S.-A. Lee, M. A. B. Casel, S.-G. Jang, S. Kim, W. Jung, C.-J. Lai, Y. K. Choi, J. U. Jung

This study develops a RBD-based nanoparticle vaccine against SARS-CoV-2 that protects ferrets from infection and reduces viral load.

bioRxiv · Jan 28, 2021Immunology

Weak catch bonds make strong networks

Y. Mulla, M. J. Avellaneda, A. Roland, L. Baldauf, W. Jung, T. Kim, S. J. Tans, G. Koenderink

This paper shows that weak catch bonds in cytoskeletal networks enhance mechanical strength and deformability by enabling dissociation-on-demand, contrasting with the traditional strength-on-demand model.

bioRxiv · Jul 27, 2020Biophysics

Mechanical stress compromises multicomponent efflux complexes in bacteria

L. A. Genova, M. F. Roberts, Y.-C. Wong, C. E. Harper, A. G. Santiago, B. Fu, A. Srivastava, W. Jung, L. M. Wang, Łukasz Krzeminski, X. Mao, X. Sun, C.-Y. Hui, P. Chen, C. Hernandez

The paper shows mechanical stress, specifically shear stress, disrupts the CusCBA efflux complex in E. coli, increasing metal toxicity susceptibility.

bioRxiv · Mar 8, 2019Biophysics

Biphasic unbinding of Zur from DNA for transcription (de)repression in Live Bacteria

W. Jung, P. Chen

This study reveals that Zur, a zinc-responsive regulator, exhibits biphasic unbinding from DNA in live E. coli, challenging existing paradigms of transcriptional repression and activation.

bioRxiv · Oct 4, 2018Biophysics