BioengineeringbioRxivPreprint
Base Editing Rescue of Seizures and SUDEP in SCN8A Developmental Epileptic Encephalopathy
Caeley M Reever, Alexis R. Boscia, Tyler C J Deutsch…·Manoj K. Patel
This study uses base editing to correct the SCN8A R1872W mutation in mice, reducing seizures and improving survival and comorbidities.
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