PhysiologyNature CommunicationsPeer-reviewed
Substrate-Specific Function of PNPLA3 Facilitates Hepatic VLDL-Triglyceride Secretion During Stimulated Lipogenesis
Scott M. Johnson, Hanmei Bao, Cailin E. McMahon…·Jun Liu
This study defines the physiological role of wild-type PNPLA3 in maintaining hepatic VLDL-TG secretion and shows that the I148M variant impairs this function during lipogenic conditions.
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