Cancer BiologyLeukemiaPeer-reviewed
Loss of thymocyte competition underlies the tumor suppressive functions of the E2a transcription factor in T lymphocyte acute lymphoblastic leukemia.
Geoffrey Parriott, Emma Hegermiller, Rosemary E. Morman…·Barbara L. Kee
This study shows that E2a suppresses T-ALL by promoting T cell development and inter-thymocyte competition, preventing leukemogenesis.
1 citation