NeurosciencebioRxivPreprint
Elucidation of Amyloid-Beta's Gambit in Oligomerisation:Truncated Aβ fragments of residues Aβ1-23, Aβ1-24 and Aβ1-25 rapidly seed to form SDS-stable, low molecular weight Aβ oligomers that impair synaptic plasticity.
Beatriz Gil, Jamie L. Rose, Davide Demurtas…·Adrien W. Schmid
This study identifies truncated Aβ fragments that form SDS-stable, low molecular weight oligomers impairing synaptic plasticity and evading conventional antibodies.
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