Jessica Sordet‐Dessimoz

The paper develops a low-input spatial proteomics workflow using standard lab equipment, achieving deep proteome coverage of the choroid plexus across age and sex in mice.

The paper identifies a sexually dimorphic hepatic cycle of VLDL generation and re-uptake in mice and humans, linking VLDLR expression to cardiovascular risk.

This study identifies truncated Aβ fragments that form SDS-stable, low molecular weight oligomers impairing synaptic plasticity and evading conventional antibodies.