microRNA-21 promotes dysregulated lipid metabolism and hepatocellular carcinoma
Chad Hilton Vansant-Webb, Jessye C. Castro, Audrey Y. Su, Kiandra Hawkins, Aavrati Saxena, Jillian Wright, Richard Anthony Smith, Mario Jorge Garcia, Y. Chen, Carrie L. Barton, Chris Stubben, Ryan M. O’Connell, Gregory S. Ducker, Kimberley Jane Evason
This study identifies miR-21 as a dysregulated microRNA in MASH-HCC, showing it promotes lipid metabolic changes that contribute to hepatocarcinogenesis in zebrafish models.
Disease Models & Mechanisms · Jan 26, 2026Peer-reviewedCancer Biology