MicrobiologybioRxiv
Single molecule-level detection and long read-based phasing of epigenetic variations in bacterial methylomes
John Beaulaurier, Shijia Zhu, Robert Sebra…·Gang Fang
This paper introduces a novel SMRT sequencing framework for single molecule-level detection of DNA methylation and epigenetic phasing in bacterial methylomes, revealing improved resolution and distinct epigenetic heterogeneity.
DOI 10.1038/ncomms8438