Cancer BiologybioRxivPreprint
Loss of SHMT2 mediates 5-FU chemoresistance by inducing autophagy in colorectal cancer
Jian Chen, Guangjian Fan, Chao Xiao…·Zhihai Peng
This study shows that loss of SHMT2 promotes 5-FU resistance in CRC by inducing autophagy through p53 regulation.
DOI 10.1101/680892